The Grey Sloan Memorial Hospital doctors are faced with the devastation left by the storm. A giant mudslide in Seattle injures a group of first responders and citizens, causing the already shorthanded ER to spring into action.
Meanwhile, Meredith is faced with a tough decision that will affect the life of a loved one, Callie is rocked by the reality of Arizona's infidelity, and Richard's life is in extreme danger.
In the second episode, the fight continues to save those affected by the storm, Callie makes a bold decision regarding her relationship, and the doctors come together upon receiving devastating news.
Season 10 stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Kevin McKidd as Owen Hunt, Jessica Capshaw as Arizona Robbins, Jesse Williams as Jackson Avery and Sarah Drew as April Kepner.
Grey's Anatomy was created and is executive-produced by Shonda Rhimes. Betsy Beers, Mark Gordon, Tony Phelan, Joan Rater and Rob Corn are executive producers. Grey's Anatomy is an ABC Studios production.