Grey's Anatomy is an American television medical drama series created by Shonda Rhimes which revolves around Dr. Meredith Grey, who began the show as a surgical intern at the fictional Seattle Grace Hospital in Seattle, Washington.
Just before Meredith Grey begins her surgical residency at Seattle Grace, she has a one night stand with her new boss, Dr. Derek Shepherd. Just call this brilliant neurosurgeon "McDreamy."
Mer's future "person," Cristina Yang, strikes up a relationship with cardiothoracic ace Preston Burke. Other interns include ex-model Izzie Stevens and her insecure BFF George O'Malley, who is branded "007" by the obnoxious Alex Karev because he has a license to kill.
Dr. Miranda Bailey keeps the interns in line while Chief Richard Webber keeps the hospital running.
Derek's wife, Addison, makes things awkward for Meredith, who must come clean that her mom is the brilliant surgeon/Alzheimer's victim, Ellis Grey. Izzie hooks up with Alex before falling for heart transplant patient Denny Duquette.
George engages in a disastrous pairing with Meredith, who later hooks up with a hot veterinarian named Finn. Burke is shot. Surgery leaves him with tremors in his hand.
Izzie cuts Denny's LVAD wire to move him up on the heart transplant list, but he dies in her arms. Izzie quits the program and Meredith must choose between Derek and Finn.
Dr. Mark Sloan makes things McSteamy at Seattle Grace. Orthopedic surgeon Callie Torres strikes up a relationship with George. Cristina covers for Burke, who hides his hand tremors.
There's a race to win the Chief's job once Richard announces retirement plans. Burke leaves Cristina on their wedding day. George loses his dad, proposes to Callie and hooks up with Izzie.
Meredith has a near-death experience and must deal with the actual death of her estranged dad's new wife. Derek tells Meredith she's the love of his life and she, in turn, lets him know that it's over. So over.
George repeats his intern year. Joining him is Little Grey, as in Meredith's half-sister, Lexie. The "really old guy" comes out of his coma. George and Izzie have bad sex.
Cristina butts heads with new cardio doc Erica Hahn, who becomes intimate with Callie. Derek and Meredith have an uphill climb with their clinical trial, but they eventually "save a life."
The two of them meet at Derek's patch of land. Meredith sets up a dazzling array of candles outlining where their house will be.
Dr. Owen Hunt is a military doc who catches Cristina's eye. He becomes the hospital's head trauma surgeon. Dr. Arizona Robbins also arrives as the new paediatric surgeon.
Mark and Lexie are a couple. Derek must overcome his shaken confidence to operate on Izzie, who has a brain tumour. He also preps for his wedding with Meredith via blue Post-It.
In the season finale, a mangled man is brought in to the hospital after jumping in front of a bus to save a woman. He writes "007" on Meredith's hand. She knows instantly that this dying hero is George.
The docs mourn the loss of one of their own — George O'Malley. Izzie recovers from brain surgery. Derek is the new Chief as Seattle Grace merges with Mercy West.
New docs on the block include Jackson Avery and April Kepner. Cardiothoracic surgeon Teddy Altman has a past with Owen, who suffers from PTSD.
A madman goes on a shooting rampage at the hospital. Many are wounded. Many are killed. The shooter tracks down his ultimate target, Dr. Derek Shepherd, and guns him down.
A distraught, pregnant Meredith miscarries as the love of her life fights to survive.
The surviving staff deals with the aftermath of the shooting tragedy. Cristina has a tough time coming back from the trauma. Derek wants to cure Alzheimer's with his clinical trial.
Callie becomes pregnant with Mark's child. She suffers major injuries after a car crash which leads to a major musical event. Callie recovers to marry Arizona.
Alex initiates a program to bring sick African kids to the States. Meredith and Derek begin their quest to adopt baby Zola. Teddy marries patient Henry so he can get on her insurance.
Cristina finds out she's pregnant and Owen is furious when he's left out of her decision to have an abortion.
Meredith loses her job because she altered the Alzheimer's clinical trial, but she's ultimately reinstated. April is the new Chief Resident.
Teddy falls for her faux husband, Henry, who dies after escalating health issues. She eventually takes a job with the U.S. Army Medical Command.
Richard must come to terms with Adele's Alzheimer's as her performs his 10,000th surgery. A plane crash leaves several docs fighting for their lives with not everyone surviving.
The surgeons cope with the loss of Lexie. Mark also ultimately succumbs to his plane crash injuries. Arizona has difficulty adjusting to life without a leg.
Cristina takes a job at the Mayo Clinic before eventually finding her way back home. A new batch of interns arrives as the plane crash docs sue for big bucks. They eventually end up buying the hospital with a little help from Catherine Avery.
Her son, Jackson, becomes the new man in charge. He lets his colleagues know that their workplace is now known as Grey + Sloan Memorial Hospital.
The Grey Sloan Memorial Hospital doctors are faced with the devastation left by the storm. A giant mudslide in Seattle injures a group of first responders and citizens, causing the already shorthanded ER to spring into action.
Meanwhile, Meredith is faced with a tough decision that will affect the life of a loved one, Callie is rocked by the reality of Arizona's infidelity, and Richard's life is in extreme danger.
Grey's Anatomy stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Chyler Leigh as Lexie Grey, Kevin McKidd as Owen Hunt, Jessica Capshaw as Arizona Robbins and Kim Raver as Teddy Altman.
Grey's Anatomy was created and is executive-produced by Shonda Rhimes (Private Practice, Scandal). Betsy Beers (Private Practice, Scandal), Mark Gordon (Saving Private Ryan), Tony Phelan, Joan Rater and Rob Corn are executive producers.
Grey's Anatomy is an ABC Studios production.