Upon learning about her illness, Cathy decided it was her turn to act up, confronting her immature husband, spoiled son and her selectively homeless and wildly outspoken brother.
She formed new, unlikely bonds with her grouchy neighbour Marlene, saucy student Andrea and neurotic friend Rebecca. She also decided to forgo treatment and live her life to the fullest each day.
But once the truth came out about her diagnosis and Marlene suddenly took her own life, Cathy changed her mind. The first season ended with Cathy submitting to a grueling experimental treatment whose outcome is far from certain.
The series focuses on Cathy Jamison (Linney), a reserved, suburban wife/mother/teacher whose terminal cancer diagnosis forces her to shake up her life and find the light side of a dark situation.
The Big C was created and written by Darlene Hunt, who serves as executive producer, along with writer/showrunner Jenny Bicks, Laura Linney, Neal H. Moritz and Vivian Cannon. It was produced by Sony Pictures Television.