Patricia Arquette is an American actress best known for her roles in such feature films as True Romance (1993), Ed Wood (1994) and Stigmata (1999); and for her starring role as Allison Dubois in the supernatural drama television series Medium, from 2005-2011.
Arquette received the Emmy in the Outstanding Lead Actress in a Drama Series category after the telecast of the initial 16 episodes of Medium.
The granddaughter of comedian Cliff Arquette (best known for his TV personality Charlie Weaver), Arquette was born in Chicago and raised in Los Angeles. Her father was actor Lewis Arquette and her siblings - Rosanna, Alexis, Richmond and David Arquette - are all actors.
Arquette's feature film credits include Richard Linklater's 12 Year Movie a.k.a. Boyhood (in which the life of a boy is shot from the first grade through high school graduation), Andrew Davis' Holes (starring opposite Sigourney Weaver and Jon Voight), Michel Gondry's Human Nature, The Badge (opposite Billy Bob Thornton), and Little Nicky (opposite Adam Sandler).
Arquette has worked with a stellar list of directors in such critically acclaimed films as: Martin Scorsese's Bringing Out the Dead (opposite Nicolas Cage), Rupert Wainwright's Stigmata (opposite Gabriel Byrne), Sean Penn's The Indian Runner, John Madden's Ethan Frome, Tony Scott's True Romance, Tim Burton's Ed Wood, David O. Russell's Flirting With Disaster, John Boorman's Beyond Rangoon, Lost Highway (in a dual role for David Lynch), Steven Frears' Hi Lo Country and Roland Jaffe's Goodbye Lover.
Among Arquette's TV movie credits is Wildflower, directed by Diane Keaton (for which Arquette earned a CableAce Award as Best Lead Actress).