With a blend of cutting-edge medical technology and topical women's issues, Strong Medicine is a one-hour drama which centres on two physicians, Dr. Luisa Delgado and Dr. Dylan West at Philadelphia's Rittenhouse Hospital.
While the strong-willed physicians come from completely opposite worlds and disagree on almost every issue, they are just as passionate in their approach to medicine.
It's this common ground that allows them to successfully work along side one another and maintain mutual respect for each other's beliefs.
With different moral, legal and ethical sides to every medical case, the two driven doctors battle fervently and rightly on issues close to them.
This season, the show continues to address cutting edge health issues as seen through the eyes of Dr. Lu Delgado, who runs the Rittenhouse Women's Health Clinic in Philadelphia.
However, for the first time since she came to the clinic, Lu has to make an adjustment ... her new partner is a man, Dr. Dylan West.
Dr. West is also someone Lu considers to be a nemesis. They tangled in medical school when he was the chief surgical resident and she was an intern on his rotation.
As talented in the field of women's health as he is brash, West is a necessary addition to the clinic, but Lu has no reason to believe he is going to be any easier to work with, or that he has what it takes to serve beside her.
But what Lu doesn't know is that Dr. West, with his California surfer mentality, has changed in some very significant and surprising ways.
And while they may have very differing viewpoints and clashing styles that could create an unwelcome administrative upheaval, the man has very good reasons, both personal and professional, for having accepted the job at Rittenhouse.
Dr. West has no intention of revealing his secrets, and even though he respects Lu and understands they are now partners, he's just fine with picking up their relationship where they left off - he enjoys pushing her buttons, and he still knows exactly where to find them.
In addition to Lu's struggle to accept Dr. West into her world, this single working mother is also struggling with whether or not she wants to make a significant change in her personal life.
As last season came to a close, she had accepted a ring from her wealthy fiancé, Jonas Rey, and is still trying to decide if she can see herself married to him.
She could never have imagined as a young Latina who grew up in Philly's inner city, driven by her memories of how tough it was for poor families to receive good medical care, that she could be marrying a multi-millionaire.
Accepting her new life with Jonas is not as easy a decision as she thought it would be.