Mandisa Nduna is a South African actress best known for her starring role as Thuli in the eKasi+ drama series Hustle.
She first rose to fame as one of the final four contestants on the second season of the SABC1 reality competition series Class Act, in 2011. Her and Pallance Dladla lost out to Tumie Ngumla and Abdul Khoza in the grand final, which aired on Saturday 16 July, 2011.
Mandisa starred alongside Siyabonga Radebe in the feature film Between Friends (2014), about a group of university friends reunite at an up-market game lodge in KwaZulu-Natal.
In the same year she starred with an all-female cast in the stage production of Animal Farm, Neil Coppen's adaption of the novel. The production had runs at The Playhouse in Durban in 2014 and at The Market Theatre in Johannesburg the following year.
Also in 2014, she starred in an episode of the e.tv drama anthology series eKasi: Our Stories entitled "Tough at the Top" (Season 5, Episode 28) as Pinky, an over-ambitious aspiring model who wants to be famous at all costs. She decides that the easiest way to the top and is to make headlines by faking her own kidnapping together with her boyfriend.
In 2015 she starred in the Mzansi Magic original movie Thank You Miss, about a passionate teacher who has to go against a society deeply entrenched in traditional patriarchal principles to save a promising learner from the custom of 'ukuthwala'. The telefilm first aired on Mzansi magic on Saturday 23 January, 2015.
In 2016 she landed her first starring role in television in the eKasi+ drama Hustle, which follows a has-been diva (Brenda Ngxoli) as she begins what will prove to be a tough journey back to the top of the charts.