Forensic Pathologist Dr. Nikki Alexander (Emilia Fox), Forensic Scientist Jack Hodgson (David Caves) and Forensic Lab Scientist Clarissa Mullery (Liz Carr) return for Season 17 of Silent Witness, but this time there's a new head of The Lyell Centre - Forensic Pathologist Dr. Thomas Chamberlain (Richard Lintern).
Chamberlain's confidence and political nose make him a good choice to lead the Lyell Centre after the death of Leo Dalton, but his sudden arrival and new approach is met by a frosty reception from Nikki, Jack and Clarissa.
It's not long before his judgment is called into question, but how quickly will Thomas be able to prove his worth?
In the opening episode, Premiership footballer Isaac Dreyfus finds his days at the top are numbered when a sex tape links him to the brutal murder of a young woman, threatening to destroy his reputation and marriage.
Dreyfus desperately fights to prove his innocence, while disillusioned Adam Freedman turns to a mysterious source for help to avenge the murder of his wife and child.
Nikki struggles to come to terms with Leo's death following the arrival of the new Lyell Centre boss, pathologist Thomas Chamberlain. However, her feelings surface when DI John Leighton and DS Anne Burchett demand results in the two unsolved cases.
When Nikki questions the motive behind the murders, a re-examination of the Freedman crime scene leads Jack to make a startling discovery.
Emilia Fox plays Dr. Nikki Alexander, David Caves plays Jack Hodgson, Richard Lintern plays Dr. Thomas Chamberlain, Liz Carr plays Clarissa Mullery, Hugo Becker plays Isaac Dreyfus, Adrian Rawlins play DI Leighton, Kaye Wragg plays DS Burchett, Ace Bhatti plays Mousa Rashid, Heida Reed plays Monica and David Fleeshman plays Jacob Ezra.
In addition, Natalie Cruceru plays Zara, Elliot Levey plays Adam Freedman, Tim Dantay plays Ron McNally, Nitin Kundra plays Bazza Numan, Shane Zaza plays Sami Rashid, Shani Erez plays Ruth, Paul Marc David plays Benjamin, Alex Norton plays Preston and Lucy Horton-Jones plays Peridita Avery.