Nurse Jackie stars Edie Falco in her Emmy Award-winning role as Jackie Peyton, a strong-willed and brilliant - but very flawed - emergency room nurse.
In Season 5, Jackie and Kevin's divorce is finalised and she begins a new relationship with a cop, all while struggling to remain sober.
Zoey and Jackie become better friends after O'Hara returns to England to raise her baby and a new head of the ER is hired, Dr. Prentiss, who has an unorthodox medical background.
Coop tangles with a hot but incompetent new intern, Akalitus deals with memory loss and Grace rebels in a big way, leading to a showdown between Jackie and Kevin.
The series also stars Merritt Wever, Paul Schulze, Dominic Fumusa, Anna Deavere Smith and Peter Facinelli. Bobby Cannavale and Morris Chestnut are season five's special guest stars. Stephen Wallem, Betty Gilpin and Adam Ferrara are guest stars.
Emmy Award nominee Clyde Phillips serves as showrunner and executive producer. Caryn Mandabach, Richie Jackson and Tom Straw also serve as executive producers.