Raised in Wilmette, Illinois, Joel Murray is the youngest in a family of nine.
He made his feature film debut in One Crazy Summer, opposite fellow Chicago actor John Cusack, and starred in the HBO film Long Gone with William L. Petersen and Virginia Madsen.
In 1989 Murray had his first starring role in the television series Grand. He spent the next two seasons playing opposite Robert Guillaume on the sitcom Pacific Station, as the highly unqualified police captain Kenny Epstein.
In 1992 Murray began a three-year stint as sanitation worker Ray Litvak on Love and War, with Annie Potts and Jay Thomas. During this period he also played parts in several feature films, including Men Will Be Boys, Scrooged, The Cable Guy, Only You, Shakes The Clown and One Crazy Summer.
In 1998, Murray joined the cast of the popular series Dharma & Greg.
He has made guest appearances on numerous other television shows including Joan Of Arcadia, The Nanny, Malcolm In The Middle, Blossom, 3-South, Partners, Mr. & Mrs. Smith, John Doe and Buzz Lightyear of Star Command.
Murray is also a voice-over artist and for 11 years was the voice of Chester the Cheetah for Cheetos.
He also voiced cartoon character Beethoven the Dog in the popular animated series and was a character voice on Baby Blues.
Murray currently lives in Los Angeles.