Eliza Coupe is an American actress and comedienne best known for her starring role as Dr. Denise "Jo" Mahoney in the medical dramedy series Scrubs, in which she became a regular for the ninth season, as well as its accompanying web series Scrubs: Interns, in 2009.
Eliza first got industry notice in 2006, when her hilarious and irreverent one-woman show which she performed at UCB/NYC was chosen to be presented at HBO's prestigious U.S. Comedy Arts Festival in Aspen.
Eliza won the Jury Award for Breakout Act of 2006. That same month she was also featured in Variety as one of the "Top 10 to Watch" in comedy.
Soon after the festival, Eliza was cast in the feature I Think I Love My Wife, directed by and starring Chris Rock. She also joined the commercial campaign for Sierra Mist, alongside Jim Gaffigan, Michael Ian Black and Tracy Morgan.
In 2007, Linda Bloodworth Thomason cast Eliza as one of the leads in her new series for HBO, 12 Miles of Bad Road, as Gaylor Shakespeare, the youngest daughter of Lily Tomlin's insane and ridiculously rich Texan family.
Eliza guest-starred on HBO's Flight of the Conchords and on ABC's Samantha Who?, Fox's Unhitched and the USA Network's Royal Pains.
In 2008, after a meeting with Bill Lawrence, she was given an 11-episode arc on Scrubs. When the show was renewed for a ninth season, she was added as a series regular.
Eliza is originally from Plymouth, NH and has a BFA in Theatre from California Institute of the Arts. She has also studied at the Groundlings Theater in LA and lives in New York City.